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Imaging the hallmarks of cancer | Nature Reviews Cancer

Notably, LBP has been shown to mitigate the pathological changes of mitochondria, protect RCG morphology and ultrastructure, inhibit neuronal apoptosis, and prevent the transition from nerve to vascular injury via its antioxidant properties, suggesting a potential therapeutic role in early-stage DR intervention (96) (Figure 6)

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A practical approach to avoid or minimize withdrawal is a test dose reduction, using the patient’s response to determine further steps